Reversal of Rotating Behavior in the Domestic Fowl by Neural Grafting

The present study was designed to establish a model of rotational behavior and its reversal through the use of neural grafting in the domestic fowl. Young sexually mature males of the chicken breed Black Silkie were utilized in this study. An initial experiment was conducted in order to select the appropriate drug for the induction of locomotor activity. Apomorphine induced locomotor activity in naive animals at a level of more than 100 times that found in control animals. The drug was effective even at low dosages and reached its maximal effect at 10 mgNg. On the other hand, unlike the results of similar treatment in rodents, amphetamine at any dosage level (from 0.25 to 40 mg/kg) produced no effect on locomotor activity in domestic fowl.